🧬 Peptide 101: Growth Hormone Secretagogues

🧬 Peptide 101: Growth Hormone Secretagogues

Scientific Breakdown:

Growth hormone (GH) secretagogues are peptides that stimulate your body’s natural GH production. They fall into two main categories:

🔹 GHRH analogs (target the hypothalamus → pituitary axis):

• Sermorelin – short-acting, mimics natural GHRH

• CJC-1295 – longer-acting, often paired with GHRP

• Tesamorelin – FDA-approved for HIV-related fat redistribution

🔹 GHRP analogs (bind ghrelin receptors on the pituitary):

• Ipamorelin – gentle, selective GH release

• GHRP-2 / GHRP-6 – stronger, but may raise cortisol/prolactin

• MK-677 – oral, long-acting, mimics ghrelin

These are often stacked (e.g., CJC-1295 + Ipamorelin) to mimic natural GH pulses and maximize effect.

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Simplified Version:

💡 What does this mean for you?

These peptides help your body make more growth hormone naturally. That can support:

• Better recovery from workouts 🏋️‍♂️

• Improved sleep 😴

• Fat loss and lean muscle gain 💪

• Healthier skin, hair, and joints ✨

Some work quickly and fade fast (like sermorelin), while others last longer and are taken less often (like CJC-1295 or MK-677). Stacking two types together often gives better results with fewer side effects.